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In addition, modulation of the expression or function of this gene may be useful in the treatment of behavioural and reproductive disorders

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Initially, the pathogenesis of NASH was explained by the “2-hit hypothesis”, where the first hit, hepatic triglyceride accumulation (steatosis), increases the liver’s susceptibility to injury from second hits, such as inflammatory cytokines, mitochondrial dysfunction, and oxidative stress [37,38]